The graphical user interface (GUI) is a native Microsoft Windows application that can also be used on Mac OS X. The command line Mega is available as native applications for Windows, Linux, and Mac OS X. They are intended for use in high-throughput and scripted analysis. Both versions are available from www.megasoftware.net free of charge. IVisTMSA is a software package of seven graphical tools for multiple sequence alignments. MSApad is an editing and analysis tool. It can load 409% more data than Jalview, STRAP, CINEMA, and Base.
This software isfreeware or shareware, only for Macintosh computers! Clicking on thelinks below will start the downloadDNA Strider
A bit dated but still great full featured sequence manipulation application for the mac. Freeware | Amplify v1.2
This software is for use in designing, analyzing, and simulating experiments involving the polymerase chain reaction (PCR). Given a template sequence and two primers, it will predict the possible outputs of the PCR, taking into account also weak matches to the target sequence. Freeware, thanks to Bill Engels | DNAid v1.8
As the author says, 'DNAid is not a heavyweight package which will run your 'just-sequenced gene' through every prediction or analysis algorithm in the known universe.' However, it is a very usefull application that allows to perform all the basic manipulations of DNA sequences such as restriction mapping, translation, reverse-complement and others. Freeware, thanks to Frédéric Dardel | MacPlasmap v1.8.2
It draws, stores, and prints high-quality circular plasmid maps with the data you specify. Fully functional. Shareware! Please read the enclosed documents before using the application | Primers! v1.0
Primers! is a very popular Macintosh utility to aid scientists in picking precisely the PCR oligos which fit their needs.Imput the target sequence and a range of selection, and Primers! will sugest the best PCR primers to amplify the selected region. Shareware at your discretion, thanks to Richard J. Resnick (Apple Pi Software). Please read the 'Read Me' file before using the application. Requires any Macintosh with a Color monitor and System 7 or beyond. | RasMac v2.6
RasMac is the Mac version of RasMol, a molecular graphics freeware program intended for the visualisation of proteins, nucleic acids and small molecules, written by Roger Sayle.You can downlod structural coordinates for a molecule of your choice -FOR INSTANCE HERE-and view, rotate and customize the look of the molecule right on your Mac even with no structural biology background (Thank you Roger Sayle!). Great for educational purposes. An excellent web site maintained by Eric Martz, for download and informations on RasMol and CHIME, a RasMol version designed as browser plug-in, can be found HERE. Before using RasMac, please read the enclosed 'Notice' file | SeqView v1.0.1
SeqVu is an alignment editor with analysis options that allows you to work quickly and simply with multiple sequences. It is ideal for manually correcting and obtaining publication-quality pictures from alignments produced using alignment software such as ClustalV or GCG pileup. Fully functional. Shareware. | Speakquencer v1.4
Speakquencer is a tool for entering and/or verifying nucleotide or amino acid sequence information. The application reads pre-existing sequences or speaks sequence as it is entered form the keyboard. Freeware, thanks to Christian Fritze | Swiss-PdbViewer 4.1 (Macos, Linux, Windows)
Free Molecular visualization software by Nicolas Guex and Manuel C. Peitsch. Swiss-PdbViewer is an application that provides a user friendly interface allowing to analyse several proteins at the same time. The proteins can be superimposed in order to deduce structural alignments and compare their active sites or any other relevant parts. Amino acid mutations, H-bonds, angles and distances between atoms are easy to obtain thanks to the intuitive graphic and menu interface. For informations, tutorials, and to download the viewer for other platforms (PC, SGI, Linux) visit the Swiss PdbViewer official site at expasy. |
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Sanger Sequencing Analysis Tools
Sequence Scanner
Downloadother Molecular Biology applications from the MB Shortcuts/JustBio softwaresection
Sequence Analysis Software Free Mac Online
In addition to the classical restriction maps - both graphic and text-based - or site usage windows, you will be able to quickly extract a sub-sequence either in a selection or between restriction sites, to create a new PCR-based fragment or synthetic adaptors. shRNA constructions based on pre-defined scaffolds are also automated. Finally, you can assemble fragments, obtained by PCR, adaptor/shRNA synthesis or simply by graphically selecting fragments between restriction sites. Just select, blunt if you need, and click the Ligate button. An additional interface allows easy Gateway(tm) cloning for both BP and LR reactions. Finally, Serial Cloner provides an interface to align two sequences using a local algorithm or the BLAST2Seq NCBI server. Features are now visible when aligning locally. You will also find a Restriction Enzyme library management interface, Additional tools, like a web browser for direct import of NCBI and EMBL entries, a virtual cutter to prepare restriction analysis or a silent restriction map generator to find how to introduce restriction sites without modifying the translated peptide are also provided. It is also posible to send directly BLAST request at the NCBI and obtain the result inside a Web interface. Serial Cloner 2.5 now allows to import codon frequency tables from the internet using a Web interface. It also allows to generate sense and antisense sequences to be obtained after bi-sulfite conversion.